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OpenUrlCrossRefPubMedWeb of Science PreviousNext Back to top View this article with LENS Vol 48 Issue 3 Table of Contents Table of ContentsTable of Contents (PDF)About the CoverIndex by author Email Thank you for your interest in spreading the word on European Respiratory Society.

In the last hundred years, lung cancer has risen from a reportable disease to the most common cause of death from cancer in both men and women in developed countries (1). When descriptions of lung cancer were published in 1912, there were only 374 reported cases (2).

In the 1950s, little more than the chest radiograph and sputum cytologic analysis were available for lung cancer screening. Since then, the mortality from lung cancer has decreased, but the 5-y cure rates have barely improved (1).

The annual number of deaths from lung cancer is greater than the numbers of deaths from breast, colon, and prostate cancers combined. More than 150,000 patients died of lung cancer in 2004. The association of lung cancer with tobacco smoking was initially reported in the 1950s (3) and subsequently led to the determination by the U.

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